Melanotan 2
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A tan, a drive, and an appetite that finally works in your favour. All from one peptide.
Melanotan II wasn't designed to do everything it does. Developed in the 1980s by University of Arizona researchers looking for a sunless tanning agent, what they found was something far more interesting — a compound 1,000 times more potent than the body's natural alpha-MSH, with tanning, appetite suppression, and aphrodisiac effects all confirmed in clinical trials and preliminary studies. Mdorthospecialists
Three outcomes. One weekly protocol.
Why MT2 belongs in your stack
Most people are dealing with at least one of three things: they want a better tan without destroying their skin with UV exposure, their libido isn't where it used to be, or their appetite is working against their body composition goals. MT2 addresses all three through the same mechanism — binding to melanocortin receptors in the skin and brain that regulate pigmentation, sexual function, and energy balance simultaneously.
It's not a stimulant. It's not a hormone. It's a signalling peptide that activates systems your body already has — and gets results that are hard to replicate any other way.
A tan that builds from the inside
Subcutaneous administration of MT2 at low doses has been shown to produce visible tanning within days — without prolonged sun exposure. MT2 selectively binds to the MC1 receptor, which regulates the conversion of tyrosine into eumelanin — the brown-to-black pigment that absorbs UV rays and actively protects epidermal cells from oxidative stress. The result is a deep, even, natural-looking tan that develops progressively and holds with minimal sun exposure to activate it. PeptideDeckPeptideDeck
Libido and sexual function restored
In a clinical study, erections developed in 8 out of 10 men treated with MT2, with a mean duration of tip rigidity above 80% of 38 minutes — compared to 3 minutes in the placebo group. The mechanism is direct: MT2 binds to MC4 receptors, which govern sexual behaviour and male erectile function — producing results that are among the most consistent and noticeable of any peptide in this category. gohighlevelRWA Center
Appetite suppression that supports fat loss
MT2 also stimulates MC3 receptors, which are involved in the regulation of appetite and energy — meaning reduced hunger is a built-in effect of the protocol, not a separate intervention. For anyone running a body composition or fat loss goal alongside their tanning protocol, this is a meaningful secondary benefit that compounds results over time. RWA Center
The research behind it
Clinical studies involving MT2 have investigated its ability to decrease appetite, increase libido, and treat male erectile dysfunction — with consistent findings across all three areas. While MT2 has not progressed through standard drug approval pathways, the breadth and consistency of its preclinical and clinical research makes it one of the most extensively studied peptides in the melanocortin space. RWA Center
How to use it
MT2 is supplied as a lyophilised powder for reconstitution with bacteriostatic water. Once mixed, it is administered via subcutaneous injection — typically into the abdomen.
Dosage Guide
| Goal | Dose | Frequency |
|---|---|---|
| Loading phase (first 1–2 weeks) | 0.25–0.5 mg | Daily or every other day |
| Maintenance phase | 0.5–1 mg | 2–3x per week |
| Tanning activation | Pair doses with brief UV exposure (10–15 min) to accelerate melanin activation |
Protocol notes:
- Start at the lower end of dosing to assess tolerance — nausea is the most common initial side effect and typically resolves after the first few doses
- Once your desired tan is achieved, maintenance doses keep it without daily dosing
- Store reconstituted vials refrigerated and use within 30 days